Radiology Teaching Files > Case 2756977

Contributed by: Kristi Takaki, Resident, Virginia Mason Medical Center, Washington, USA.
Patient: 3 month old male
History: 3 month full term baby. Parents noted baby didn't track or smile. Presented with seizures at 2 months old.

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Lissencephaly is lack of sulcation of the gyri as a result of incomplete neuroblastic migration to the superficial layers of the cortex during twelfth to the twenty-second week of pregnancy.

Chromosome X involvement have frontal lobe predominance.
Chromosome 17 involvement predominantly affects the parietal lobe.

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Additional Details:

Case Number: 2756977Last Updated: 2011-06-29
Anatomy: Cranium and Contents   Pathology: Congenital
Modality: MRAccess Level: Readable by all users

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