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Fig. 1: Axial T2WI in this 4 y.o. shows minimal myelination in internal capsules

Fig. 2: More superior images show lack of myelination in peripheral white matter

Fig. 3: The lack of myelination on T2WI would be appropriate for a child 10 months or younger.

Fig. 4: For comparison, this is the normal pattern of myelination seen in a 3.5 y.o. Note that myelinated white matter is hypointense in signal on T2WI

Fig. 5: Sagittal T1WI shows normal pattern of myelination in the corpus callosum.

Fig. 6: Off-midline sagittal T1WI shows good myelination as bright white matter signal in the peripheral braches of white matter. Children typically achive this degree of myelination by about 8-10 months.

Fig. 7: Follow up MR exam performed when this child was 9 years old shows only minor progression of myelination
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