MyPACS.net: Radiology Teaching Files > Case 2756977

Never visited LISSENCEPHALY
Contributed by: Kristi Takaki, Resident, Virginia Mason Medical Center, Washington, USA.
Patient: 3 month old male
History: 3 month full term baby. Parents noted baby didn't track or smile. Presented with seizures at 2 months old.
Images:[small]larger

Fig. 1

Fig. 2

Fig. 3

Fig. 4
Discussion:

Lissencephaly is lack of sulcation of the gyri as a result of incomplete neuroblastic migration to the superficial layers of the cortex during twelfth to the twenty-second week of pregnancy.

Chromosome X involvement have frontal lobe predominance.
Chromosome 17 involvement predominantly affects the parietal lobe.

Comments:
No comments posted.
Additional Details:

Case Number: 2756977Last Updated: 2011-06-29
Anatomy: Cranium and Contents   Pathology: Congenital
Modality: MRAccess Level: Readable by all users

The reader is fully responsible for confirming the accuracy of this content.
Text and images may be copyrighted by the case author or institution.
You can help keep MyPACS tidy: if you notice a case which is not useful (e.g. a test case) or inaccurate, please contact us.