| Findings: Chest X-ray: 1. Increased density and widening of superior mediastinum, predominant over left side, nature to be determined (figure 1).
Multidetector row CT scan of chest with pre- and post-intravenous contrast, and with multiplanar reconstruction, maximum-intensity projection, and 3D volume rendering: 1. A lobulated big mass with punctate calcifications (figure 2, arrows) and mild contrast enhancement (figure 3) in bilateral paraspinal regions of posterior mediastinum, predominant over left side, neurogenic tumor such as thoracic neuroblastoma may be considered until proved otherwise. 2. Suspicious spinal canal invasion by the tumor with mild erosion of posterior surfaces of corresponding vertebral bodies in upper thoracic spine (figure 3, red arrow). 3. Presence of mass effect of the above tumor with direct indentation of left-sided descending aorta (figure 4 and 5, yellow arrows) and indirect compression of left bronchus (figure 4-6, blue arrows) with significant smooth stenosis. 4. Some passive atelectasis in both lungs due to mass effect of the tumor. 5. Small subpleural infiltration in both lower lungs, may due to chronic inflammatory process. Impression: 1. Posterior mediastinum tumor, suspicious neurogenic tumor. 2. Suspicious tumor invasion to thoracic spinal canal. 1.5 Tesla MRI of chest (focus on thoracic spine) with MR myelography, T2 weighted echo train spin echo, T1 weighted echo train spin echo with and without fat saturation, MR diffusion imaging, T2/T1 steady-state gradient echo with fat saturation, and with intravenous gadolinium-enhancement:
1. A lobulated big long T1 and T2 mass with strong contrast enhancement (figure 7, red arrows) and without significant restricted water diffusibility (not showed) in bilateral paraspinal regions of posterior mediastinum, predominant over left side, neurogenic tumor such as thoracic neuroblastoma may be considered until proved otherwise. 2. Presence of tumor direct invasion to T1-T5 dilated spinal canal through bilateral neuroforamina (figure 7, yellow arrows). Mass effect of the tumor with encasement and compression of corresponding spinal cord (figure 8, arrows). But no detectable signal change or contrast enhancement within spinal cord itself. 3. Besides, tumor direct extension to midline posterior back soft tissue and left paravertebral back muscles (figure 7, green arrows). 4. A 1.1cm ovoid enhancing nodule in right infraspinatus muscle over right upper back, suggesting tumor distal metastasis (figure 9, red arrows). 5. Some small lymph nodes in bilateral axillae, may due to chronic infection. Impression: 1. Posterior mediastinum tumor, suspicious neurogenic tumor. 2. Tumor invasion to T1-T5 spinal canal with corresponding spinal cord compression. 3. Besides tumor direct invasion to left back muscle and distal metastasis to right back muscle. |