| Findings: Initial Brain Ultrasound (fig.1-2): 1. Hyperechoic change of left corpus striatum (red arrows in fig.1, 2) and corona radiata (yellow arrow in fig.1) without midline shift.
MRI of brain (5 days later) with T1 weighted echo train spin echo, T2 weighted echo train spin echo, fluid-attenuated inversion recovery echo train spin echo, MR diffusion imaging, short inversion time inversion recovery echo train spin echo, time-of- flight MR angiogarphy with 3D maximum-intensity projection reconstruction, and without intravenous contrast (fig.3-9): 1. Lobulated long T2 change (red arrows in fig.4,5) with significant restricted water diffusibility (red arrows in fig.7,8) in left corpus striatum, at least including caudate nucleus and both anterior (yellow arrows in fig.7,8) and posterior (green arrows in fig.7,8) limbs of internal capsule, and extension into medial (blue arrows in fig.7,8) and middle (pink arrows in fig.7,8) base of left cerebral peduncle in midbrain, suggesting neonatal brain infarction with at least left deep cerebral nuclei and corticospinal and frontopontine tracts involvement. 2. Focal heterogeneous short T1 and dark T2 (orange arrows in fig3-6) change within the lesion at left lentiform nucleus and corona radiata, in favor of post infarction hemorrhagic transformation with intracellular methemoglobin accumulation. 3. No detectable abnormal finding in intracranial arteries, including left middle cerebral artery (red arrow in fig.9).
Follow up brain ultrasound with power Doppler images (fig.10-12): 1. Decreased the high echogenic signal in left corpus striatum (red arrows in fig.10) compared to previous ultrasound (fig.1). 2. No detectable abnormal finding in intracranial arteries, including left middle cerebral artery (red arrow in fig.11). |